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Fig. 7 | BMC Biology

Fig. 7

From: mTORC1/AMPK responses define a core gene set for developmental cell fate switching

Fig. 7

Assay for developmental abnormality to discover novel genes forming essential core for early development. a Normal early multi-cell development is observed for null cells from the unclassified starvation-alone induced gene group (see Fig. 5b). Mutant cells were plated and observed for multi-cell aggregation and induction of developmental marker-CAR1 expression after 5 h of starvation under developmental buffer. b Mutant cells from the unclassified rapamycin-induced class (see Fig. 5b) were unable to initiate multi-cell formation. Mutant cells were plated for multi-cell aggregation and assayed for induction of developmental marker-CAR1 expression after 5 h of starvation under developmental buffer. All lines remained as single cells and did not induce developmental gene expression

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