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Table 2 I-TASSER GO/functional predictions for unclassified, rapamycin-induced genes that regulate development (see Fig. 7b, Table 1)

From: mTORC1/AMPK responses define a core gene set for developmental cell fate switching

Gene ID and protein size Biological function Molecular function Cellular component Ligand binding and homology domains
DDB_G0292188
750 amino acids
GO:0007166
Cell surface receptor signaling pathway
GO:0004888
Transmembrane signaling receptor activity
GO:0016021
Integral component of membrane
Glutamic acid; zinc
von Willebrand factor (vWF) type A domain
DDB_G0267942
898 amino acids
GO:0033365
Protein localization to organelle
GO:0005515
Protein binding
GO:0031967
Organelle envelope
Zinc
Gram domain
DDB_G0281781
620 amino acids
GO:0016477
Cell migration
GO:0004872
Signaling receptor activity
GO:0005924
Cell-substrate adherens junction
Glucose; calcium
(None)
DDB_G0269670
568 amino acids
GO:0007018
Microtubule-based movement
GO:0032559
Adenyl ribonucleotide binding
GO:0030286
Dynein complex
Zinc; magnesium; iron
C2 and WW domains
DDB_G0280921
1049 amino acids
GO:0030032
Lamellipodium assembly
GO:0005515
Protein binding
GO:0044424
Intracellular part
Zinc; magnesium; calcium
Phox homology domain
  1. Annotated protein sequences [46, 47] of characterized early Rapamycin upregulated genes (see Fig. 7b, Table 1) were analyzed by I-Tasser [48, 49]