Table 1 Significant TF-drug associations. Thirty-eight TF-drug pairs were discovered as significant at false discovery rate (FDR) of 5% (nominal p value < 0.0021). p value of the hypergeometric tests are shown in the third column. The fourth column (“Impact predictor utility p score”) shows an empirical p value for each association, computed by repeating the hypergeometric test using a size-matched random subset of SNPs within ChIP peaks (rather than SNPs with greatest TFBS-SNP impact scores) 100 times and counting how frequently the test p value in these random controls is smaller than that observed in the original test for that TF-drug pair
