Fig. 3.

Assembly process of BMCs. a Core-first assembly (beta-carboxysomes and metabolosomes). Aggregation of the core enzymes is facilitated by the encapsulation peptide in combination with other assembly proteins. After aggregation the encapsulation peptide interacts with the shell proteins to from a complete BMC. b Concomitant assembly (alpha carboxysomes): simultaneous core aggregation and shell protein recruitment is enabled by the intrinsically disordered protein CsoS2