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Fig. 1 | BMC Biology

Fig. 1

From: Cold-induced lipid dynamics and transcriptional programs in white adipose tissue

Fig. 1

Changes of the overall lipid composition and distribution in iWAT in response to cold exposure. Lipidomic analysis of iWAT isolated from mice maintained at room temperature (RT, 22 °C) or cold (4 °C) for 3 days. Lipids were extracted and analyzed as described in the “Methods” section. a Distribution of lipid classes that were considered for subsequent analysis in all of the samples detected by LC-MS/MS. b–g The intensity fold change of fatty acyls (b), glycerolipids (c), glycerophospholipids (d), sphingolipids (e), saccharolipids (f), and prenol lipids (g). Data are presented as means + SEM (n = 8). *P < 0.05, ***P < 0.001. h Log2 fold changes in lipid species in cold-treated versus RT mice and the corresponding significance values displayed as -log10 (P value). Each dot represents a lipid species, and the dot size indicates significance. Only lipids with P < 0.05 are displayed (n = 8)

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