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Fig. 3 | BMC Biology

Fig. 3

From: Cold-induced lipid dynamics and transcriptional programs in white adipose tissue

Fig. 3

Cold-mediated changes in TAG composition and fatty-acyl chains in iWAT. a The top 20 TAGs according to the P value, detected in iWAT isolated from RT- and cold-treated mice (n = 8). b The total intensity fold changes of individual fatty-acyl chains associated with TAG sorted by degree of saturation. SAF, saturated fatty acyls; MUFA, monounsaturated fatty acyls; PUFA, polyunsaturated fatty acyls containing two or three to six double bonds; ODD, odd-numbered fatty acyls. The transparency of each bar is proportional to the significance values, which are displayed as -log10 (P value). The gray bars indicate those with P > 0.05. c, d The TAG pattern in cold-treated cases versus that in controls. Each dot or triangle represents a distinct TAG, organized along the x axis based on total acyl-chain carbon number (c) or double-bond content (d). The size of each dot or triangle is proportional to the significance values, which are displayed as -log10 (P value). Only lipids with P < 0.05 are displayed. e Selected fatty acid metabolic reactions from KEGG, with indications of quantified lipid classes and fatty-acyl chains (circles) and genes (rectangles) significantly regulated in iWAT by short-term cold exposure. For other abbreviations, see Fig. 2

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