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Fig. 2. | BMC Biology

Fig. 2.

From: Changes in ESCRT-III filament geometry drive membrane remodelling and fission in silico

Fig. 2.

Transition between filament geometries creates membrane deformation. a The tilted state is defined by an angle τ, which is the angle between the radial axis and the triplet subunit axis. b Rotating the target geometry ring by a tilt angle τ (τ=60, depicted in the inset) creates downward membrane deformations, away from the cytoplasm. The curve shows the depth of the deformation over time (R=15.3 nm and lp=1.8·103 nm). c The direction of the deformation can be reversed by tilting the filament outwards, rather than inwards. The new target geometry is now a ring with τ=−40, R=11.5 nm, and lp=1.8·103 nm. The underlying curve shows the height of the developing deformation over time

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