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Fig. 1 | BMC Biology

Fig. 1

From: Transcriptome resilience predicts thermotolerance in Caenorhabditis elegans

Fig. 1

Experimental setup and expression dynamics during heat-stress perturbations. a Experimental design of the three main treatments: control (blue; 20 °C throughout development), heat stress (orange; populations shifted to 35 °C after 46 h of development at 20 °C), and recovery (purple; at 20 °C after heat stress). b A subset of samples from heat stress and control treatments was used for the inference of the heat-stress axis, H, describing the gene expression dynamics during heat stress. c Projection of the data on this axis describes the dynamics of the response to heat stress. Notably, this is true also for the recovery data that was not used to infer axis H. d Projection of transcriptome data of the recovery process after 2, 3, 4, and 6 h of heat stress shows a decrease in recovery dynamics. e Axis H also describes the transcriptional heat-stress response for strains other than N2

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