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Fig. 5. | BMC Biology

Fig. 5.

From: Multi-species annotation of transcriptome and chromatin structure in domesticated animals

Fig. 5.

Correlation between gene expression and promoter accessibility in pig. For each expressed FR-AgENCODE gene with an ATAC-seq peak in the promoter region, the Pearson correlation was computed between the base 10 logarithm of the RNA-seq gene expression (TMM) and the base 10 logarithm of the ATAC-seq chromatin accessibility (normalized by csaw). The distribution is represented for genes with no significant differential expression between liver and T cells (a, top) and for differentially expressed genes (b, bottom). The distribution obtained for differentially expressed genes showed an accumulation of both positive and negative correlation values, suggesting a mixture of regulatory mechanisms

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