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Table 4 NLR-C characteristics

From: The round goby genome provides insights into mechanisms that may facilitate biological invasions

Group Identified in this study Walker A Last residues of the largest exon PYD? B30.2?
1   GIAGVGKT L(I/M)PVVKNT(T/R)RA + +
2   GVAGIGKS LSAVIKTSKRA + +
3   GIAGIGKT L(IP/TA)AV(R/S)NC(RK/TR/RR)A +
4   GVAGIGKT LPV(I/V)xxxx(A/V)x
5 x GVAG(V/I)GKT (L/M)PV(V/I)KASxK(A/V) + +
6 x GVAGVGKT L(I/V)P(A/V)VRNCRKA
  1. Key features of each of the six NLR-C subgroups as identified from zebrafish (Danio rerio) and round goby. Each of the groups is characterized by the presence of a highly conserved Walker A Motif and either the presence or absence of specific C- and N-terminal domains (PYD and B30.2). x denotes a variable amino acid, + and − denote whether the denoted domains are characteristically present/absent in the group