Fig. 5
From: The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology
Anti-CTLA-4 antibody treatment facilitates the proliferation of Th17 cells in the LP. a, b The numbers of Tregs and Th17 cells in the LP on day 7 after treatment with the IgG antibody or anti-β7 mAb, 2.5% DSS and without (a) or with (b) CTLA-4 blockade were determined. c, d The percentages of Ki67+ Tregs and Th17 cells in the peripheral blood (c) and lamina propria (d) were determined 6 days after CTLA-4 blockade. There were 4-5 mice in each group. The data represent mean ± SEM. For all graphs: *P < 0.05, **P < 0.01 and ****P < 0.0001