Skip to main content
Fig. 6 | BMC Biology

Fig. 6

From: Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

Fig. 6

Overview of the analyses of species contribution to NMPCs. a Table of genera explaining more than 25% of the variance in metabolite NMPCs different between cases and controls. b Table of NMPCs, for which Akkermansia explained at least 25% of the variance in the total to community net production capacity. c Box plots of gamma-aminobutyrate (GABA) net production capacity for PD cases and controls (b = 0.18, 95% CI 0.06, 0.30, p = 0.003, FDR = 0.0501). d Scatter plot of GABA net production capacity in dependence of Akkermansia abundance with non-linear regression lines. NMPC, = net maximal production capacity; GABA, gamma-aminobutyrate; FDR, false discovery rate. Effect sign “–”: negative correlation. Effect sign “+”: positive correlation

Back to article page
\