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Table 1 Quantitative and qualitative expression changes in the movant strains

From: Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae

 

-35

-510

-1120

C2+479

Number of upregulated genes

2 (1)

62 (37)

361 (64)

439 (88)

Mean upregulationa

n/d

1.5 ± 0.97

0.67 ± 0.41

0.78 ± 0.56

Number of downregulated genes

6 (4)

49 (2)

301 (9)

303 (17)

Mean downregulationa

n/d

− 0.5 ± 0.24

− 0.49 ± 0.26

− 0.52 ± 0.29

Total number of altered genes

8

111 (39)

662 (72)

742 (105)

Altered functions

E, P, V

E, O, R, V, N

E, O, R, V, N, F, P, U

  1. The number of differentially expressed genes (p < 0.05) compared to parental strain in fast-growing conditions. The number in parenthesis represents genes whose expression varies more than 2-fold. The magnitude of expression change is quantified as the average of the Log2(FC) ± standard deviation
  2. aAverage of the Log2(FC) ± standard deviation. n/d not determined