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Table 1 Correlation of DNA methylation and chronological age with different targeted approaches

From: New targeted approaches for epigenetic age predictions

 

Pyrosequencing

ddPCR

BBA-seq

Training (n = 40)

Validation (n = 40)

Training (n = 40)

Validation (n = 40)

Training (n = 38)

Validation (n = 39)

FHL21

0.76

0.77

0.82

0.84

0.82

0.28

IGSF11

0.53

0.71

0.62

0.62

0.58

0.55

CCDC102B

0.56

0.7

0.72

0.68

0.60

0.58

MEIS1-AS311

0.56

0.55

0.67

0.46

0.68

0.55

ELOVL2

0.45

0.46

–

–

0.87

0.63

COL1A1

0.32

0.4

0.5

0.56

0.42

0.51

ASPA

0.29

0.57

0.43

0.56

0.37

0.57

ITGAB1

0.03

0.15

–

–

0.14

0.11

PDE4C1

0.8

0.74

0.89

0.79

0.82

0.71

Mean R2

0.48

0.56

0.66

0.64

0.59

0.50

  1. 1We have always depicted result for the CpG with the highest Pearson correlation within the amplicon. Thus, the CpGs are not always identical (Additional file 1: Table S5, S7 and S9)