Fig. 1
From: The evolution of the Puf superfamily of proteins across the tree of eukaryotes
Clustering analysis of Puf family proteins. PufSF proteins were analysed by CLANS. A total of 4469 proteins formed three major clusters of proteins corresponding to Nop9 homologues (Nop9 cluster), ‘classical’ Puf proteins (Puf cluster), and PUM3 orthologues (PUM3 cluster). The protein sequences were colour-coded according to the taxonomic affiliation to the eukaryotic supergroup. The details of each large cluster show mostly lineage-specific subclusters, except two large subclusters of Puf proteins. The diagrams above the cluster details depict the general domain arrangement of PufSF proteins; PF00806 corresponds to Puf RNA-binding repeat. The x and y axes represent relative positions of the protein sequence in 2D CLANS