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Fig. 4. | BMC Biology

Fig. 4.

From: Real-time tracking of stem cell viability, proliferation, and differentiation with autonomous bioluminescence imaging

Fig. 4.

Autobioluminescent cardiomyocytes enable kinetic doxorubicin toxicity monitoring over prolonged time periods. a CM-lux autobioluminescence pre- and post-challenge with increasing doses of doxorubicin (challenge was introduced at the time indicated by the white arrow). b Representative pseudocolor images of CM-lux autobioluminescent signal at 2.5-h intervals over the time series shown in a. c The calculated IC50 of doxorubicin plotted against time. Values are representative of N = 3 replicates. Error bars represent the standard error of the means. p/s/cm2/sr; photons/s/cm2/steradian. Data is available at https://osf.io/h5qzj/ [15]

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