Fig. 3
Composition of the gut microbiome when tumours reached 350 mm3. a Stacked bar plot of the phylogenetic composition of common bacterial taxa at the species level when tumours reached 350 mm3. Samples were collected from mice fed with low-fibre, high mixed fibre, high insoluble fibre, and high soluble fibre diets (n = 8 for each group). b–e Results for irradiated mice only. b Shannon’s index of gut microbiomes by the Kruskal-Wallis test. Error bars represent the interquartile range of diversity scores. c Principal coordinate analysis of gut microbiomes using the Bray-Curtis dissimilarity. Relative abundance of d B. acidifaciens and e Bacteroidales S24-7 in mice with or without irradiation. *p < 0.05; **p < 0.01; ***p < 0.001