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Fig. 5 | BMC Biology

Fig. 5

From: A molecular insight into the dissociable regulation of associative learning and motivation by the synaptic protein neuroligin-1

Fig. 5

Measuring motivational behavior outside an operant environment. a Open-field test. b Porsolt swim test. Nlgn1−/− mice (with previous operant experience) show decreased exploration and spontaneous locomotor activity in a novel, open-field environment. c Ambulatory distance (centimeters) (generalized linear model **p < 0.005) and d resting time (seconds) (mixed-effects linear model **p < 0.005) but no changes in e velocity (centimeters/second) (mixed-effects linear model). Values represent means ± SEM. f Nlgn1−/− mice showed increased mobility time (seconds) in the Porsolt swim test; two-way ANOVA, time bins collapsed for analysis, main effect of genotype **p < 0.005, values represent means ± SEM

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