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Fig. 8 | BMC Biology

Fig. 8

From: Spatial and temporal modulation of enterotoxigenic E. coli H10407 pathogenesis and interplay with microbiota in human gut models

Fig. 8

SCFA ratios and concentrations in the ileum and ascending colon compartments over time in the M-SHIME. SCFA concentrations displaying stability from day 7 to 12 were retained as the pre-infection period, and from day 13 to 20 as the post-infection period. a SCFA ratio was calculated as the mean acetate, propionate, and butyrate ratios of 6 donors ± SD. Statistically significant differences between pre- and post-infection periods are denoted at p < 0.05 (*) and p < 0.01 (**) as determined by pairwise Wilcoxon rank sum tests with Holm correction. b Difference in average concentrations of SCFA (mM) between pre- and post-infection periods in the ileum and ascending colon for the six donors. Following ETEC infection, a decrease of SCFA concentration is displayed in shade of blue while an increase is in shade of red. Statistically significant differences between pre- and post-infection periods are denoted at p < 0.05 (*) and p < 0.01 (**) as determined by pairwise Wilcoxon rank sum tests with Holm correction

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