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Fig. 4 | BMC Biology

Fig. 4

From: In vivo imaging of injured cortical axons reveals a rapid onset form of Wallerian degeneration

Fig. 4

Synaptic boutons delay the onset of degeneration in cortical axons. a, b Representative images of axons with relatively low (a) and high (b) densities of terminaux boutons (TBs). c, d There is a significant correlation between bouton density and the onset of fragmentation for segments undergoing WD (c, p < 0.05, n = 13 axons, 13 mice) and for shorter axons undergoing roWD (d, p < 0.01, n = 20 axons, 12 mice). e, f There is no correlation between bouton density and fragmentation rate for segments undergoing WD (e, p > 0.05) or roWD (f, p > 0.05). Scale bar 40 μm (a, b)

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