TY - JOUR AU - Donia, M. S. AU - Fischbach, M. A. PY - 2015 DA - 2015// TI - Small molecules from the human microbiota JO - Science. VL - 349 UR - https://doi.org/10.1126/science.1254766 DO - 10.1126/science.1254766 ID - Donia2015 ER - TY - JOUR AU - Bansal, T. AU - Alaniz, R. C. AU - Wood, T. K. AU - Jayaraman, A. PY - 2010 DA - 2010// TI - The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation JO - Proc Natl Acad Sci VL - 107 UR - https://doi.org/10.1073/pnas.0906112107 DO - 10.1073/pnas.0906112107 ID - Bansal2010 ER - TY - JOUR AU - Schiering, C. AU - Wincent, E. AU - Metidji, A. AU - Iseppon, A. AU - Li, Y. AU - Potocnik, A. J. PY - 2017 DA - 2017// TI - Feedback control of AHR signalling regulates intestinal immunity JO - Nature. VL - 542 UR - https://doi.org/10.1038/nature21080 DO - 10.1038/nature21080 ID - Schiering2017 ER - TY - JOUR AU - Yano, J. M. AU - Yu, K. AU - Mazmanian, S. K. AU - Hsiao Correspondence, E. Y. AU - Donaldson, G. P. AU - Shastri, G. G. PY - 2015 DA - 2015// TI - Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis JO - Cell. VL - 161 UR - https://doi.org/10.1016/j.cell.2015.02.047 DO - 10.1016/j.cell.2015.02.047 ID - Yano2015 ER - TY - JOUR AU - Bhattarai, Y. AU - Williams, B. B. AU - Battaglioli, E. J. AU - Whitaker, W. R. AU - Till, L. AU - Grover, M. PY - 2018 DA - 2018// TI - Gut microbiota-produced tryptamine activates an epithelial G-protein-coupled receptor to increase colonic secretion JO - Cell Host Microbe VL - 23 UR - https://doi.org/10.1016/j.chom.2018.05.004 DO - 10.1016/j.chom.2018.05.004 ID - Bhattarai2018 ER - TY - JOUR AU - Venkatesh, M. AU - Mukherjee, S. AU - Wang, H. AU - Li, H. AU - Sun, K. AU - Benechet, A. P. PY - 2014 DA - 2014// TI - Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and toll-like receptor 4 JO - Immunity. VL - 41 UR - https://doi.org/10.1016/j.immuni.2014.06.014 DO - 10.1016/j.immuni.2014.06.014 ID - Venkatesh2014 ER - TY - JOUR AU - Barker, H. A. PY - 1981 DA - 1981// TI - Amino acid degradation by anaerobic bacteria JO - Annu Rev Biochem VL - 50 UR - https://doi.org/10.1146/annurev.bi.50.070181.000323 DO - 10.1146/annurev.bi.50.070181.000323 ID - Barker1981 ER - TY - JOUR AU - Yvon, M. AU - Thirouin, S. AU - Rijnen, L. AU - Fromentier, D. AU - Gripon, J. PY - 1997 DA - 1997// TI - An aminotransferase from Lactococcus lactis initiates conversion of amino acids to cheese flavor compounds JO - Appl Envir Microbiol VL - 63 UR - https://doi.org/10.1128/AEM.63.2.414-419.1997 DO - 10.1128/AEM.63.2.414-419.1997 ID - Yvon1997 ER - TY - JOUR AU - Nierop Groot, M. N. AU - Bont, J. A. M. PY - 1998 DA - 1998// TI - Conversion of phenylalanine to benzaldehyde initiated by an aminotransferase in Lactobacillus plantarum JO - Appl Environ Microbiol VL - 64 UR - https://doi.org/10.1128/AEM.64.8.3009-3013.1998 DO - 10.1128/AEM.64.8.3009-3013.1998 ID - Nierop Groot1998 ER - TY - JOUR AU - Elsden, S. R. AU - Hilton, M. G. AU - Waller, J. M. PY - 1976 DA - 1976// TI - The end products of the metabolism of aromatic amino acids by clostridia JO - Arch Microbiol VL - 107 UR - https://doi.org/10.1007/BF00425340 DO - 10.1007/BF00425340 ID - Elsden1976 ER - TY - JOUR AU - Dodd, D. AU - Spitzer, M. H. AU - Treuren, W. AU - Merrill, B. D. AU - Hryckowian, A. J. AU - Higginbottom, S. K. PY - 2017 DA - 2017// TI - A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites JO - Nature. VL - 551 UR - https://doi.org/10.1038/nature24661 DO - 10.1038/nature24661 ID - Dodd2017 ER - TY - JOUR AU - Dickert, S. AU - Pierik, A. J. AU - Buckel, W. PY - 2002 DA - 2002// TI - Molecular characterization of phenyllactate dehydratase and its initiator from Clostridium sporogenes JO - Mol Microbiol VL - 44 UR - https://doi.org/10.1046/j.1365-2958.2002.02867.x DO - 10.1046/j.1365-2958.2002.02867.x ID - Dickert2002 ER - TY - JOUR AU - Dickert, S. AU - Pierik, A. J. AU - Linder, D. AU - Buckel, W. PY - 2000 DA - 2000// TI - The involvement of coenzyme A esters in the dehydration of (R)-phenyllactate to (E)-cinnamate by Clostridium sporogenes JO - Eur J Biochem VL - 267 UR - https://doi.org/10.1046/j.1432-1327.2000.01427.x DO - 10.1046/j.1432-1327.2000.01427.x ID - Dickert2000 ER - TY - JOUR AU - Kessel, S. P. AU - Frye, A. K. AU - El-Gendy, A. O. AU - Castejon, M. AU - Keshavarzian, A. AU - Dijk, G. PY - 2019 DA - 2019// TI - Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease JO - Nat Commun VL - 10 UR - https://doi.org/10.1038/s41467-019-08294-y DO - 10.1038/s41467-019-08294-y ID - Kessel2019 ER - TY - JOUR AU - Maini Rekdal, V. AU - Bess, E. N. AU - Bisanz, J. E. AU - Turnbaugh, P. J. AU - Balskus, E. P. PY - 2019 DA - 2019// TI - Discovery and inhibition of an interspecies gut bacterial pathway for levodopa metabolism JO - Science. VL - 364 UR - https://doi.org/10.1126/science.aau6323 DO - 10.1126/science.aau6323 ID - Maini Rekdal2019 ER - TY - JOUR AU - Bianchine, J. R. AU - Messiha, F. S. AU - Hsu, T. H. PY - 1972 DA - 1972// TI - Peripheral aromatic L-amino acids decarboxylase inhibitor in parkinsonism. II. Effect on metabolism of L-2- 14 C-dopa JO - Clin Pharmacol Ther VL - 13 UR - https://doi.org/10.1002/cpt1972134584 DO - 10.1002/cpt1972134584 ID - Bianchine1972 ER - TY - JOUR AU - Morgan, J. P. PY - 1971 DA - 1971// TI - Metabolism of levodopa in patients with Parkinson’s disease JO - Arch Neurol VL - 25 UR - https://doi.org/10.1001/archneur.1971.00490010049007 DO - 10.1001/archneur.1971.00490010049007 ID - Morgan1971 ER - TY - JOUR AU - Sasahara, K. AU - Nitanai, T. AU - Habara, T. AU - Kojima, T. AU - Kawahara, Y. AU - Morioka, T. PY - 1981 DA - 1981// TI - Dosage form design for improvement of bioavailability of levodopa IV: possible causes of low bioavailability of oral levodopa in dogs JO - J Pharm Sci VL - 70 UR - https://doi.org/10.1002/jps.2600700705 DO - 10.1002/jps.2600700705 ID - Sasahara1981 ER - TY - JOUR AU - Goldin, B. R. AU - Peppercorn, M. A. AU - Goldman, P. PY - 1973 DA - 1973// TI - Contributions of host and intestinal microflora in the metabolism of L-dopa by the rat JO - J Pharmacol Exp Ther VL - 186 ID - Goldin1973 ER - TY - JOUR AU - Fasano, A. AU - Visanji, N. P. AU - Liu, L. W. C. AU - Lang, A. E. AU - Pfeiffer, R. F. PY - 2015 DA - 2015// TI - Gastrointestinal dysfunction in Parkinson’s disease JO - Lancet Neurol VL - 14 UR - https://doi.org/10.1016/S1474-4422(15)00007-1 DO - 10.1016/S1474-4422(15)00007-1 ID - Fasano2015 ER - TY - JOUR AU - Panagamuwa, B. AU - Kumar, D. AU - Ortiz, J. AU - Keighley, M. R. B. PY - 1994 DA - 1994// TI - Motor abnormalities in the terminal ileum of patients with chronic idiopathic constipation JO - Br J Surg VL - 81 UR - https://doi.org/10.1002/bjs.1800811142 DO - 10.1002/bjs.1800811142 ID - Panagamuwa1994 ER - TY - JOUR AU - Sijp, J. R. M. AU - Kamm, M. A. AU - Nightingale, J. M. D. AU - Britton, K. E. AU - Granowska, M. AU - Mather, S. J. PY - 1993 DA - 1993// TI - Disturbed gastric and small bowel transit in severe idiopathic constipation JO - Dig Dis Sci VL - 38 UR - https://doi.org/10.1007/BF01295909 DO - 10.1007/BF01295909 ID - Sijp1993 ER - TY - JOUR AU - Dutkiewicz, J. AU - Szlufik, S. AU - Nieciecki, M. AU - Charzyńska, I. AU - Królicki, L. AU - Smektała, P. PY - 2015 DA - 2015// TI - Small intestine dysfunction in Parkinson’s disease JO - J Neural Transm VL - 122 UR - https://doi.org/10.1007/s00702-015-1442-0 DO - 10.1007/s00702-015-1442-0 ID - Dutkiewicz2015 ER - TY - JOUR AU - Knudsen, K. AU - Haase, A. M. AU - Fedorova, T. D. AU - Bekker, A. C. AU - Ostergaard, K. AU - Krogh, K. PY - 2017 DA - 2017// TI - Gastrointestinal transit time in Parkinson’s disease using a magnetic tracking system JO - J Parkinsons Dis VL - 7 UR - https://doi.org/10.3233/JPD-171131 DO - 10.3233/JPD-171131 ID - Knudsen2017 ER - TY - JOUR AU - Das, Y. T. AU - Bagchi, M. AU - Bagchi, D. AU - Preuss, H. G. PY - 2004 DA - 2004// TI - Safety of 5-hydroxy-L-tryptophan JO - Toxicol Lett VL - 150 UR - https://doi.org/10.1016/j.toxlet.2003.12.070 DO - 10.1016/j.toxlet.2003.12.070 ID - Das2004 ER - TY - JOUR AU - Heap, J. T. AU - Kuehne, S. A. AU - Ehsaan, M. AU - Cartman, S. T. AU - Cooksley, C. M. AU - Scott, J. C. PY - 2010 DA - 2010// TI - The ClosTron: mutagenesis in Clostridium refined and streamlined JO - J Microbiol Methods VL - 80 UR - https://doi.org/10.1016/j.mimet.2009.10.018 DO - 10.1016/j.mimet.2009.10.018 ID - Heap2010 ER - TY - JOUR AU - Roager, H. M. AU - Hansen, L. B. S. AU - Bahl, M. I. AU - Frandsen, H. L. AU - Carvalho, V. AU - Gøbel, R. J. PY - 2016 DA - 2016// TI - Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut JO - Nat Microbiol VL - 1 UR - https://doi.org/10.1038/nmicrobiol.2016.93 DO - 10.1038/nmicrobiol.2016.93 ID - Roager2016 ER - TY - JOUR AU - Iwamoto, K. AU - Watanabe, J. AU - Yamada, M. AU - Atsumi, F. AU - Matsushita, T. PY - 1987 DA - 1987// TI - Effect of age on gastrointestinal and hepatic first-pass effects of levodopa in rats JO - J Pharm Pharmacol VL - 39 UR - https://doi.org/10.1111/j.2042-7158.1987.tb03413.x DO - 10.1111/j.2042-7158.1987.tb03413.x ID - Iwamoto1987 ER - TY - JOUR AU - Zoetendal, E. G. AU - Raes, J. AU - Bogert, B. AU - Arumugam, M. AU - Booijink, C. C. AU - Troost, F. J. PY - 2012 DA - 2012// TI - The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates JO - ISME J VL - 6 UR - https://doi.org/10.1038/ismej.2011.212 DO - 10.1038/ismej.2011.212 ID - Zoetendal2012 ER - TY - JOUR AU - Booijink, C. C. G. M. AU - El-Aidy, S. AU - Rajilić-Stojanović, M. AU - Heilig, H. G. H. J. AU - Troost, F. J. AU - Smidt, H. PY - 2010 DA - 2010// TI - High temporal and inter-individual variation detected in the human ileal microbiota JO - Environ Microbiol VL - 12 UR - https://doi.org/10.1111/j.1462-2920.2010.02294.x DO - 10.1111/j.1462-2920.2010.02294.x ID - Booijink2010 ER - TY - JOUR AU - Costa, M. AU - Brookes, S. J. AU - Hennig, G. W. PY - 2000 DA - 2000// TI - Anatomy and physiology of the enteric nervous system JO - Gut VL - 47 UR - https://doi.org/10.1136/gut.47.suppl_4.iv15 DO - 10.1136/gut.47.suppl_4.iv15 ID - Costa2000 ER - TY - JOUR AU - Ringdahl, B. PY - 1986 DA - 1986// TI - Dissociation constants and relative efficacies of acetylcholine, (+)- and (-)-methacholine at muscarinic receptors in the guinea-pig ileum JO - Br J Pharmacol VL - 89 UR - https://doi.org/10.1111/j.1476-5381.1986.tb11115.x DO - 10.1111/j.1476-5381.1986.tb11115.x ID - Ringdahl1986 ER - TY - JOUR AU - Jenner, A. M. AU - Rafter, J. AU - Halliwell, B. PY - 2005 DA - 2005// TI - Human fecal water content of phenolics: the extent of colonic exposure to aromatic compounds JO - Free Radic Biol Med VL - 38 UR - https://doi.org/10.1016/j.freeradbiomed.2004.11.020 DO - 10.1016/j.freeradbiomed.2004.11.020 ID - Jenner2005 ER - TY - JOUR AU - Keshavarzian, A. AU - Green, S. J. AU - Engen, P. A. AU - Voigt, R. M. AU - Naqib, A. AU - Forsyth, C. B. PY - 2015 DA - 2015// TI - Colonic bacterial composition in Parkinson’s disease JO - Mov Disord VL - 30 UR - https://doi.org/10.1002/mds.26307 DO - 10.1002/mds.26307 ID - Keshavarzian2015 ER - TY - JOUR AU - Jin, J. S. AU - Hattori, M. PY - 2012 DA - 2012// TI - Isolation and characterization of a human intestinal bacterium Eggerthella sp. CAT-1 capable of cleaving the C-Ring of (+)-catechin and (-)-Epicatechin, followed by p-dehydroxylation of the B-ring JO - Biol Pharm Bull VL - 35 UR - https://doi.org/10.1248/bpb.b12-00726 DO - 10.1248/bpb.b12-00726 ID - Jin2012 ER - TY - JOUR AU - Haiser, H. J. AU - Gootenberg, D. B. AU - Chatman, K. AU - Sirasani, G. AU - Balskus, E. P. AU - Turnbaugh, P. J. PY - 2013 DA - 2013// TI - Predicting and manipulating cardiac drug inactivation by the human gut bacterium Eggerthella lenta JO - Science. VL - 341 UR - https://doi.org/10.1126/science.1235872 DO - 10.1126/science.1235872 ID - Haiser2013 ER - TY - STD TI - Kalia VC, Mukherjee T, Bhushan A, Joshi J, Shankar P, Huma N. Analysis of the unexplored features of rrs (16S rDNA) of the genus Clostridium. BMC Genomics. 2011;12. https://doi.org/10.1186/1471-2164-12-18. ID - ref37 ER - TY - JOUR AU - Niehues, M. AU - Hensel, A. PY - 2009 DA - 2009// TI - In-vitro interaction of L-dopa with bacterial adhesins of Helicobacter pylori: an explanation for clinicial differences in bioavailability? JO - J Pharm Pharmacol VL - 61 UR - https://doi.org/10.1211/jpp/61.10.0005 DO - 10.1211/jpp/61.10.0005 ID - Niehues2009 ER - TY - JOUR AU - Zimmermann, M. AU - Zimmermann-Kogadeeva, M. AU - Wegmann, R. AU - Goodman, A. L. PY - 2019 DA - 2019// TI - Separating host and microbiome contributions to drug pharmacokinetics and toxicity JO - Science. VL - 363 UR - https://doi.org/10.1126/science.aat9931 DO - 10.1126/science.aat9931 ID - Zimmermann2019 ER - TY - JOUR AU - Williams, B. B. AU - Benschoten, A. H. AU - Cimermancic, P. AU - Donia, M. S. AU - Zimmermann, M. AU - Taketani, M. PY - 2014 DA - 2014// TI - Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine JO - Cell Host Microbe VL - 16 UR - https://doi.org/10.1016/j.chom.2014.09.001 DO - 10.1016/j.chom.2014.09.001 ID - Williams2014 ER - TY - JOUR AU - Lucchelli, A. AU - Boselli, C. AU - Grana, E. PY - 1990 DA - 1990// TI - Dopamine-induced relaxation of the guinea-pig isolated jejunum is not mediated through dopamine receptors JO - Pharmacol Res VL - 22 UR - https://doi.org/10.1016/1043-6618(90)90750-8 DO - 10.1016/1043-6618(90)90750-8 ID - Lucchelli1990 ER - TY - STD TI - Heap JT, Pennington OJ, Cartman ST, Carter GP, Minton NP. The ClosTron: a universal gene knock-out system for the genus Clostridium 2007;70:452–464. doi:https://doi.org/10.1016/j.mimet.2007.05.021. ID - ref42 ER - TY - JOUR AU - Heap, J. T. AU - Pennington, O. J. AU - Cartman, S. T. AU - Minton, N. P. PY - 2009 DA - 2009// TI - A modular system for Clostridium shuttle plasmids JO - J Microbiol Methods VL - 78 UR - https://doi.org/10.1016/j.mimet.2009.05.004 DO - 10.1016/j.mimet.2009.05.004 ID - Heap2009 ER - TY - JOUR AU - Williams, D. R. AU - Young, D. I. AU - Young, M. PY - 1990 DA - 1990// TI - Conjugative plasmid transfer from Escherichia coli to Clostridium acetobutylicum JO - J Gen Microbiol VL - 136 UR - https://doi.org/10.1099/00221287-136-5-819 DO - 10.1099/00221287-136-5-819 ID - Williams1990 ER - TY - JOUR AU - Nagatsu, T. AU - Kojima, K. PY - 1988 DA - 1988// TI - Application of electrochemical detection in high-performance liquid chromatography to the assay of biologically active compounds JO - TrAC Trends Anal Chem VL - 7 UR - https://doi.org/10.1016/0165-9936(88)80026-8 DO - 10.1016/0165-9936(88)80026-8 ID - Nagatsu1988 ER - TY - JOUR AU - Wood, D. E. AU - Lu, J. AU - Langmead, B. PY - 2019 DA - 2019// TI - Improved metagenomic analysis with Kraken 2 JO - Genome Biol VL - 20 UR - https://doi.org/10.1186/s13059-019-1891-0 DO - 10.1186/s13059-019-1891-0 ID - Wood2019 ER - TY - JOUR AU - Lu, J. AU - Breitwieser, F. P. AU - Thielen, P. AU - Salzberg, S. L. PY - 2017 DA - 2017// TI - Bracken: estimating species abundance in metagenomics data JO - PeerJ Comput Sci VL - 2017 UR - https://doi.org/10.7717/peerj-cs.104 DO - 10.7717/peerj-cs.104 ID - Lu2017 ER -