Fig. 7

Phyletic distributions of classes of EVE fusion proteins with predicted roles in prokaryotic modification-dependent restriction and toxin-antitoxin systems. The most common classes of EVE fusion proteins in prokaryotes, with one representative chosen per genus. The representatives contain the core elements depicted (not to scale), with additional domains often present, especially in EVE-McrB proteins. The dotted lines with an arrow at each end indicate that the EVE domain can occur in either position, but not both