Skip to main content

Table 1 Highest confidence (95%) changes in homecage gene expression in CBPKIX/KIX mice

From: The CBP KIX domain regulates long-term memory and circadian activity

Gene symbol Confidence Probe set Molecular role Wt(Log2) % change
Downregulated genes
 Slc25a34 0.995 1455506_at Mitochondrial solute carrier protein 7.99 − 43%
 Papss2## 0.995 1421987_at Sulfate Adenylyltransferase, cysteine synthesis 6.89 − 42%
 Efcab6 0.993 1453766_a_at Calcium-binding transcriptional co-repressor 8.02 − 25%
 Cbp 0.993 1459804_at Transcriptional co-activator CBP, KIX domain 8.41 − 37%
 Nts 0.991 1422860_at Neuropeptide 10.73 − 31%
 Lipm# 0.991 1430550_at Triglyceride hydrolysis 5.38 − 40%
 Cenpa 0.991 1450842_a_at Double-strand break repair, centromere organization 6.75 − 29%
 Pmch 0.988 1429361_at Neuropeptide 7.33 − 24%
 Fos 0.988 1423100_at DNA-binding transcription factor 9.55 − 33%
 Crhbp 0.988 1436127_at Regulator of hormone signaling 11.03 − 20%
 Ccl6# 0.988 1420249_s_at Cytokine, inflammatory response 6.79 − 25%
 Cth 0.987 1426243_at Cysteine-Protein Sulfhydrase, cysteine synthesis 7.89 − 24%
 Nqo1 0.98 1423627_at Positive regulator of translation; quinone detoxification 9.27 − 20%
 Tbx1 0.975 1425779_a_at DNA-binding transcription factor 5.65 −25%
 Spata13 0.975 1454656_at Guanine nucleotide exchange factor 9.44 − 19%
 Rec8 0.975 1419147_at Meiotic chromatid cohesion 6.68 − 26%
 Bglap 0.972 1449880_s_at Osteogenic marker 7.13 − 38%
 Cyp11a1# 0.965 1448804_at Steriod hormone metabolism, cholesterol metabolism 7.43 − 28%
 Pdlim2 0.962 1423946_at Negative regulator of NFkappa-B and STAT signaling 9.46 − 21%
 Zdbf2 0.955 1456783_at Unknown 10.51 − 16%
 Pcsk1 0.955 1421396_at Pro-neuropeptide cleavage 7.91 − 24%
 Gpnmb 0.955 1448303_at Transmembrane glycoprotein 7.84 − 18%
 Dusp10 0.955 1417163_at Phosphatase 8.96 − 17%
 Dbp# 0.955 1418174_at DNA-binding transcription factor 10.63 − 24%
 Plcd1 0.952 1448432_at Ca2+-dependent phospholipase, phosphotidyl inositol-signaling 8.69 − 18%
 Mmel1 0.952 1449432_a_at Membrane metalloprotease 5.17 − 28%
 Cort 0.952 1449820_at Neuropeptide 9.01 − 30%
Upregulated genes
 Ifi27l2a 0.995 1427747_a_at Interferon, alpha-inducible protein 27 like 2A 2.19 358%
  1. #A second probe set for this gene was also present in the 80% confidence probe set list
  2. ##Two additional probe sets for this gene were present in the 80% confidence probe set list