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Fig. 10 | BMC Biology

Fig. 10

From: Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy

Fig. 10

The switching hooks of PCNA for fixing conformation of PolD. a The Form A observed in our EM analysis. b The Form B observed in our EM analysis. The 3′-terminus of DNA can reach the active center of the exonuclease in DP1. The Form A and Form B can correspond to synthesis mode and editing mode, respectively. c The Form B can also form an intermediate state in the switching process from PolD to the next factor on the PCNA ring

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