Fig. 6.
From: Crystal structure of the yeast heterodimeric ADAT2/3 deaminase
The tRNA deamination activity test of ScADAT3/V121M and the structural basis for disease. a The deamination assays on WT and ScADAT3/V121M. b The surrounding environment of ScADAT3/Val121. The residues that may establish hydrophobic contacts with Val121 are shown and labeled. c The potential steric clashes in the modeled ScADAT3/V121M mutant