Fig. 8
From: Horizontally acquired antibacterial genes associated with adaptive radiation of ladybird beetles
The consistent retention of cwh genes from the beginning of angiosperm dominance is considered relevant to the adaptive radiation of ladybirds. A phylogenetic study of ladybird Coccinellidae and Coleoptera outgroups based on 819 single-copy genes and 12 fossil calibration points revealed crown diversification of the ladybird subfamily Coccinellinae approximately 110 million years ago (MYA). Most of the Coccinellinae species contain both cwh1 (red disc) and cwh2 (blue disc). Details of the tree can be found in Additional file 1: Figs. S7 and S8