Fig. 5
From: Putative ligand binding sites of two functionally characterized bark beetle odorant receptors
Protein model of ItypOR49. Left image: overview model indicating the predicted binding cavity in red mesh. Residues lining this cavity which in previous studies have been shown to affect ligand binding are shown in stick representation. Transmembrane (TM) helix 7 that forms the ion channel in the tetrameric Orco complex is located to the right. The expected extension of the lipid bilayer is indicated by gray lines. Right image: closer view of the cavity in the transmembrane region. Predicted binding site I and II as well as TM domains 2–4 and extracellular loop (EL) 2 are indicated