Fig. 6
From: Putative ligand binding sites of two functionally characterized bark beetle odorant receptors
Results from molecular docking analysis. Predicted binding of (R)-(+)-ipsenol (purple) and (S)-(−)-ipsenol (yellow) to a ItypOR46 (site I) and b ItypOR49 (site II). Predicted binding of (R)-(−)-ipsdienol (rose) and (S)-(+)-ipsdienol (green) to c ItypOR46 (site I) and d ItypOR49 (site II). Binding site I is located approximately midway in the transmembrane region in relation to the plasma membrane. The shallower predicted binding site II is near the extracellular opening of the binding cavity. Potential hydrogen bonds are indicated with dashed lines. Residues in ORs that adopt a new position upon docking of a ligand are colored according to the corresponding ligand