The draft nuclear genome sequence and predicted mitochondrial proteome of Andalucia godoyi, a protist with the most gene-rich and bacteria-like mitochondrial genome

Table 3 Factors involved in the assembly of ETC Complexes I–V

Complex I		Complex II		Complex III		Complex IV		Complex V
Hsa	Ago	Hsa	Ago	Hsa	Ago^b	Hsa	Ago^b	Hsa	Ago	Sce
NUBPL	NUBPL	SDHAF1	SdhAF1	MZM1L	LYRM7	CMC1	Cmc1	ATPAF1	Atp11
NDUFAF2	NDUFAF2	SDHAF2	SdhAF2	BCS1L	n.d.	CMC2	Cmc2	ATPAF2	Atp12
NDUFAF3	NDUFAF3	SDHAF3	SdhAF3	UQCC1	Cbp3	COA1	n.d.	ATP23	Atp23
NDUFAF4	n.d.	SDHAF4	SdhAF4	UQCC2	n.d.	(COA2^c)	n.d.	TMEM70	n.d.
NDUFAF5	NDUFAF5			UQCC3	n.d.	COA3	n.d.
NDUFAF6	NDUFAF6			TTC19	n.d.	COA4	Coa4		Atp10	Atp10
NDUFAF7	NDUFAF7					COA5	Coa5		Nca2	Nca2
NDUFAF8	n.d.			–	CcmA	COA6	Coa6
NDUFAF1^a	NDUFAF1			–	CcmB	COA7	n.d.
TIMMDC1	n.d.			–	CcmC	COX10	Cox10
ECSIT	n.d.			–	CcmD	COX11	Cox11
ACAD9	n.d.			–	CcmE	COX14	n.d.
TMEM126B	n.d.			–	CcmF	COX15	Cox15
TMEM186	n.d.			–	CcmG	COX16	Cox16
FOXRED1	n.d.			–	CcmH	COX17	Cox17
ATP5SL	n.d.			–	CcmI	COX18	Cox18
DMAC1	DMAC1					COX19	Cox19
COA1	n.d.					COX20	Cox20
TMEM70	n.d.					COX23	Cox23
AIF	AIF^e					PET100	Pet100F^d
						PET117	Pet117
						TACO1	Taco1
						FASTKD2	n.d.
						SCO1 / 2	Sco
						SURF1	Surf1/Shy1

See HGNC (mitochondrial respiratory chain complex assembly factors) [59], Guerrero-Castillo et al. [56], and Signes and Fernandez-Vizarra [58]. n.d., not detected
^aGenes set in italics are members of the Mitochondrial Complex I Assembly (MCIA) complex (see [60])
^bGenes set in bold are encoded in the A. godoyi mitochondrial genome
^cExclusively fungal; no human ortholog
^dFungal version
^eListed under (I) ROS METABOLISM, REGULATION in Additional file 1: Table S1

ISSN: 1741-7007