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Fig. 4 | BMC Biology

Fig. 4

From: Evolution of metabolic capabilities and molecular features of diplonemids, kinetoplastids, and euglenids

Fig. 4

Presence/absence patterns of the proteins involved in the trypanothione biosynthesis and utilization in Euglenozoa. Gene presence, absence from a genome, absence from a transcriptome, and presence of a partial/divergent sequence are indicated with blue, black, gray, and blue hatched circles, respectively. Putative evolutionary gain/loss events of three thiol-redox systems in Euglenozoa are shown with white circles. Enzymes’ abbreviations are as follows: ARG, arginase; CBS, cystathionine β-synthetase; CGL, cystathionine γ-lyase; CS, cysteine synthetase; GR, glutathione reductase; GshA, γ-glutamyl-cysteine synthetase; GshB, glutathione synthetase; GspS, glutathionylspermidine synthetase; ODC, ornithine decarboxylase; SAT, serine acetyltransferase; SpS, spermidine synthetase; TR, trypanothione reductase; TrxR, thioredoxin reductase; TryS, trypanothione synthetase. Rev. trans., reverse trans-sulfuration pathway

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