Fig. 2From: Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populationsComparison of model predictions to Wolbachia field trial data from Yorkeys Knob and Gordonvale, Australia. Field observations of Wolbachia population frequency are depicted in light blue, with 95% binomial confidence intervals based on the frequency and sample size reported for the 2011 field trials in Yorkeys Knob and Gordonvale [21]. Model predictions are depicted for an analogous release scheme consisting of 20 Wolbachia-infected mosquitoes (10 female and 10 male) per household at a coverage of 30% over 10 weeks with the exception that in Gordonvale, the fifth release was postponed by a week due to a tropical cyclone. Parameter values listed in Additional file 1: Table S1. Wolbachia infection is associated with a 10% fitness cost. Agreement between observations and predictions is strong, providing good validation of the modeling frameworkBack to article page