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Fig. 2 | BMC Biology

Fig. 2

From: Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations

Fig. 2

Comparison of model predictions to Wolbachia field trial data from Yorkeys Knob and Gordonvale, Australia. Field observations of Wolbachia population frequency are depicted in light blue, with 95% binomial confidence intervals based on the frequency and sample size reported for the 2011 field trials in Yorkeys Knob and Gordonvale [21]. Model predictions are depicted for an analogous release scheme consisting of 20 Wolbachia-infected mosquitoes (10 female and 10 male) per household at a coverage of 30% over 10 weeks with the exception that in Gordonvale, the fifth release was postponed by a week due to a tropical cyclone. Parameter values listed in Additional file 1: Table S1. Wolbachia infection is associated with a 10% fitness cost. Agreement between observations and predictions is strong, providing good validation of the modeling framework

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