Fig. 2

Examples of rRF-producing hotspots. a–c Shown are regions from 28S rRNA (a), 16S rRNA (b), and 5S rRNA (c). Each heatmap depicts the relative abundance of rRFs across all of the 434 LCL samples that map to the region of interest. Each adjacent boxplot displays the distribution of start and end positions of rRFs for the region shown in the heatmap. The heatmaps are scaled by row (sample). d Each reference rRNA (GenBank) is shown as a rectangle with solid blue contour. The solid black vertical line denotes position 1 of the reference rRNAs. Observed endpoints of x-rRFs that map immediately upstream or downstream of the reference rRNA sequences are represented by yellow boxes. Reference rRNA transcript locations that are adjacent to the nominal endpoints and did not have any rRFs mapping to them are shown with empty boxes with dashed lines. Not drawn to scale