Fig. 4
Numerous rRFs are differentially abundant by sex and population origin. a The number of instances where SAM identified an rRF as differentially abundant is shown in yellow (FDR ≤ 0.01). The number of instances where PLS-DA identified an rRF as differentially abundant is shown in green (VIP ≥ 1.5). The intersection of the two circles shows the number of comparisons where both SAM and PLS-DA found the same rRF to be differentially abundant. Also shown is the Jaccard index of the comparisons that are found to be differentially abundant by the two methods. b The Jaccard index for each rRNA is plotted against the median RPM of the iDARs. c For the iDARs, log2 fold change was plotted as a function of significance (q-value) for each of the 10 population combinations, and separately for males and females. The key at the bottom shows the q-value distribution in each of the 10 intervals that represent a population vs. population comparison