TY - JOUR AU - Szymura, Szymon J. AU - Bernal, Giovanna M. AU - Wu, Longtao AU - Zhang, Zhongqin AU - Crawley, Clayton D. AU - Voce, David J. AU - Campbell, Paige-Ashley AU - Ranoa, Diana E. AU - Weichselbaum, Ralph R. AU - Yamini, Bakhtiar PY - 2020 DA - 2020/03/24 TI - DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy JO - BMC Biology SP - 32 VL - 18 IS - 1 AB - Nuclear factor-κB (NF-κB) plays a prominent role in promoting inflammation and resistance to DNA damaging therapy. We searched for proteins that modulate the NF-κB response as a prerequisite to identifying novel factors that affect sensitivity to DNA damaging chemotherapy. SN - 1741-7007 UR - https://doi.org/10.1186/s12915-020-0764-z DO - 10.1186/s12915-020-0764-z ID - Szymura2020 ER -