Fig. 5

Overview of mechanical modes of wound response in Stentor. Conceptual illustration of mechanical response modes in Stentor described in this study. a An unwounded cell is bisected into 2 wounded cell fragments using our microfluidic guillotine platform. After wounding, Stentor can potentially use a combination of 3 mechanical response modes to aid in its wound repair: b contraction, in which the cell folds around the wound site, c cytoplasm retrieval, in which extruded cytoplasm is pulled back into the cell body, and d twisting/pulling, in which the cell uses a twisting/pulling motion to detach from extruded cytoplasm. Further work is needed to probe the mechanisms of these wound response modes and to investigate the wound repair mechanisms in Stentor