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Table 1 Number of immune-related gene family members from sequenced Dipteran genomes, annotated by hidden Markov models

From: The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control

  Scal Mdom Gmor Aaeg Dmel
Canonical pattern recognition
 Nimorod (NIM) 25 23 10 8 17
 Peptidoglycan recognition protein (PGRP) 17 17 4 10 13
 beta-1,3-glucan-binding proteins (BGBP) 4 3 3 7 7
 Thioester containing proteins (TEP) 16 22 4 8 6
Other recognition
 C-type lectin (CTL) 78 41 11 43 38
 Fibrinogen-related proteins (FREP) 49 38 7 34 14
 Galectins (GALE) 15 13 8 12 6
 Immunoglobulin superfamily (IGSF) 1 1 1 0 1
 MD2-like proteins (MD2L) 8 12 5 26 8
 Scavenger receptor class A (SRCA) 3 3 2 2 3
 Scavenger receptor class B (SRCB) 15 18 11 13 14
 Scavenger receptor class C (SRCC) 7 8 4 5 9
Canonical effectors
 Attacin antimicrobial peptides (ATT) 11 (12)* 10 4 1 4
 Defensin antimicrobial peptides (DEF) 5 (11)* 5 0 4 1
 Diptericin antimicrobial peptides (DIPT) 3 (1)* 4 0 1 3
 Cecropin antimicrobial peptides (CEC) 5 (10)* 12 2 9 5
 Lysozymes (LYS) 23 32 4 7 13
Non-canonical effectors
 Thioredoxin peroxidases (TPX) 5 6 6 5 8
 Prophenoloxidases (PPO) 19 23 4 25 10
 Glutathione peroxidases (GPX) 1 1 0 3 2
 Heme peroxidases (HPX) 12 12 8 19 10
 Transferrins (TSF) 4 6 3 5 3
  1. *Numbers in parentheses are those numbers annotated after manual curation of the S. calcitrans genome. Scal: Stomoxys calcitrans, Mdom: Musca domestica, Gmor: Glossina morsitans, Aaeg: Aedes aegypti, Dmel: Drosophila melanogaster