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Fig. 2 | BMC Biology

Fig. 2

From: Waking experience modulates sleep need in mice

Fig. 2

The effect of voluntary wheel running on sleep EEG spectra and SWA. a Average NREM EEG spectra of the first hour of recovery sleep after the wheel running (RW) and exploratory wakefulness (EW) conditions. Shaded areas depict standard errors of the mean. Horizontal lines denote frequency bins where EEG power was different between RW and EW conditions (black: p < 0.05, grey: p < 0.1, Wilcoxon rank sum tests). b Cortical EEG slow-wave activity (0.5–4 Hz EEG band) during recovery NREM sleep after RW and EW. Points represent average SWA of individual animals shown in hourly bins, depicted as percentage of average SWA of preceding baseline day (frontal EEG: mixed-model ANOVA (factors hour, condition) on log-transformed data showed statistically significant effect of hour (F (5, 40)=27.97, p < 0.0001), but no effect of condition (F (1, 8)< 1, p = 1) and no statistically significant interaction (F (5, 40)=0.93, p = 0.47)). Occipital EEG: data were not normally distributed, yet neither transformed nor original data yielded a statistically significant effect of condition or a significant interaction between hour and condition (mixed-model ANOVA on log-transformed data: statistically significant effect of hour (F (5, 50)=31.6, p < 0.0001) yet no effect of experimental condition (F (1, 10)=2.6, p = 0.14) or interaction (F (5, 50)=1.2, p = 0.33); the same test on non-transformed data: significant effect of hour (F (5, 50)=33.7, p < 0.0001), no significant effect of experimental condition (F (1, 10)=1.4, p = 0.15) and no significant interaction (F (5, 50)=1.13, p = 0.36))

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