Fig. 4
From: H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner
Overexpression of utx-1 enhances resistance to oxidative, UV and heat stressors. Animals were either exposed to 10 mM paraquat from L4 onwards to induce oxidative stress (a), given a 1000-Jm−2 dose of UVC 3 days post-L4 to induce UV stress (b), or exposed to 35 °C heat for 6 h from 5 days post-L4 to induce heat stress (c), and scored for survival. In all cases, animals overexpressing utx-1 (red survival curve) were more resistant to stress compared to control worms containing the same co-injection marker (rol-6+) (blue survival curve) (all ****p < 0.0001) (see Additional file 10: Table S6 for the full statistical analysis of lifespan data, including repeats)