Skip to main content

Table 1 Reduced brood size of mes-2, utx-1 and jmjd-3.2 mutants is not required for lifespan extension. Single worms were picked onto separate plates and the whole brood counted by moving the mother onto a fresh plate each day until egg-laying stopped and combining the counts for each plate. The broods of a minimum of 10 animals were assessed per strain. The table is ranked by brood size. p values are relative to the wild-type N2 strain

From: H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner

Genotype

Average brood size ± SEM

p value

Significance

N2

238 ± 7

mes-2(tm5007)

231 ± 7

> 0.999

ns

utx-1(tm3118)/+

230 ± 8

0.999

ns

jmjd-3.2(tm3121)

228 ± 14

0.989

ns

mes-2(bn11)/+

176 ± 7

< 0.001

***

mes-2(bn11)

0

< 0.001

***

mes-2(ok2480)

0

< 0.001

***