Skip to main content
Fig. 1 | BMC Biology

Fig. 1

From: Chronic temperature stress inhibits reproduction and disrupts endocytosis via chaperone titration in Caenorhabditis elegans

Fig. 1

Chronic heat stress inhibits reproduction and affects global gene expression. Chronic exposure of day 1 adult N2 wild-type (WT) worms to 28 °C heat stress (HS) inhibits the number of eggs laid (a), mildly affects motility (b), and alters global gene expression (ce) compared to 20 °C control worms. Data in a and b represent mean ± SD of n = 30 worms, collected across three independent trials. ** p < 0.01, **** p < 0.0001 (Student’s t test versus 20 °C at the same timepoint). Data in ce represent densities of genes at each fold-change (log2) value relative to the 0-h (20 °C) controls following 1-h (c), 24-h (d), or 48-h (e) 28 °C HS as determined by RNA-seq analysis. Dashed vertical lines denote upper and lower expression limits of the genes that were up- or down-regulated, with the total number of differentially expressed genes in each category in parentheses. Arrows in e represent the fold-change expression of the six vit genes

Back to article page