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Table 2 Gene ontology term enrichment

From: Multi-omic profiling of pituitary thyrotropic cells and progenitors

GHFT1 cells TαT1 cells
Gene Structure and development1 Expression Gene Synapse development and function2 Expression
A B C D E GHFT1 TαT1 F G H I J GHFT1 TαT1
Cyr61 X X X X X 117.1 0.5 Nrxn1 X X X X X 0.0 4.2
Edn1 X X X X X 7.3 0.0 Unc13a X X X X X 0.0 19.8
Bmp4 X X X X X 6.8 0.0 Drd2 X X   X X 0.0 12.4
Tgfbr2 X X X X X 65.1 0.0 Chrnb2 X X   X X 0.0 12.7
Fgf10 X X X X X 1.1 0.0 Grin1 X X   X X 0.0 20.5
Gli3 X X X X X 13.4 0.0 Syt4 X X   X X 0.0 86.3
Mef2c X X X X X 7.6 0.0 Grin3a X X   X X 0.0 11.4
Cav1 X X X X X 10.1 0.0 Snap25 X X   X X 0.1 107.4
Bmp5 X X X X X 3.8 0.0 Sez6 X X X X X 0.0 39.8
Ctgf X X X X X 40.3 0.0 Gabrg2 X X X X X 0.0 13.0
Gli2 X X X X X 4.2 0.0 Pclo X X X X X 0.0 4.0
Gata6 X X X X X 1.2 0.0 Atp2b2    X X   0.0 9.4
Tbx20 X X X X X 2.2 0.0 Chrna4 X X    X 0.0 3.4
Msx2 X X X X X 20.1 0.0 Shisa6 X X    X 0.0 11.3
Yap1 X X X X X 40.3 0.2 Lrrc4c    X X   0.0 1.7
Sfrp1 X X X X X 7.1 0.0 Thy1     X   0.0 23.3
Hlx X X X X X 1.5 0.0 Glra3 X X X   X 0.0 28.1
Cxcl12 X X X X X 4.2 0.0 Adgfb1    X X   0.0 9.5
Pax3 X X X X X 9.1 0.0 Gria1 X X    X 0.0 11.7
Fn1 X X X X X 611.8 1.0 Lgi1     X   0.0 1.1
  1. 1 The top five GO terms associated with the top 5% of the most differentially expressed genes (log 2-fold-change) in GHFT1 cells are A = animal organ development, B = anatomical structure development, C = anatomical structure morphogenesis, D = multicellular organism development, E = system development. X’s illustrate the association of each gene with a GO term. Expression is given in FPKM
  2. 2 The top five GO terms associated with TαT1 cells are: F = synaptic signaling, G = trans-synaptic signaling, H = synapse organization, I = nervous system development, J = anterograde trans-synaptic signaling