Fig. 2.
Diversity of lineage graphs. A total of 4,852,994 graphs were used to generate the following figures. a Abundance of lineage graph topologies. The bar represents the fraction of graphs that have a given topology. Graphs given along the bar are examples of model-generated lineage graphs. Parameters (N,Pasym,Psig,Padj) used to generate these graphs: unicellular (3, 0, 0, 0), cyclic (4, 0.2, 0, 0.5), chain (5, 0, 0.4, 0.9), tree (6, 0, 0.4, 1), and DAG (4, 0.1, 0, 0.4). Colors indicate lineage graph topology: unicellular: dark gray; cyclic: light gray; chain: red; tree: black; and DAG: blue. b Stacked histogram for topologies of lineage graphs obtained with different N. Heights of colored blocks represent the proportions of corresponding topologies. c Distribution of basin sizes in the gene regulatory networks across different lineage graph topologies. For any given topology, the height of bars indicates the fraction of lineage graphs of that topology that were obtained using a gene regulatory network whose average basin size is given along the horizontal axis. d Stacked histogram showing distribution of number of cell types in homeostatic organisms with lineage graphs of various topologies. See also Additional file 1: Figure S9