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Fig. 5. | BMC Biology

Fig. 5.

From: Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube

Fig. 5.

Missexpression of active Notch (aN2) ventral to the prospective RP causes an ectopic upregulation of RP markers. a, d, g, j Electroporation of aN2-GFP. b, e, h, k ISH of corresponding sections. c, f, i, l Overlay of the precedent. Arrows indicate the localization of electroporated cells and arrowheads mark the ectopic upregulation of Rspo1 (N = 6/7), BAMBI (N = 7/9), Raldh2 (N = 4/6), or Draxin (5/5), respectively, within the interneuron domain. For control GFP, see Fig. 4. Bar = 50 μm

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