Skip to main content
Fig. 9 | BMC Biology

Fig. 9

From: Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility

Fig. 9

Delayed meiosis in male and female SHR rats lacking Prdm9 function. a-d Delayed prophase I in Prdm9-deficient male rats compared to controls. a, b Immunohistochemistry of 21-dpp testes (154 to 368 tubules scored from each animal). c Immunocytochemistry of 18-dpp testicular spreads (over 400 spermatocytes for each genotype). d Delayed meiosis is associated with apoptosis. Immunohistochemistry of prepubertal testes using TUNEL and DAPI. e Delayed onset of pachynema in Prdm9-deficient female rats. Spread 21-dpc ovarian nuclei were staged using immunocytochemistry (over 250 oocytes scored for each of the three Prdm9 genotypes; LRM). The data underlying all published plots are in Additional file 3

Back to article page