Fig. 5From: Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particlesPurification of virus particles by SXC. DI244 material produced in shake flasks was purified with membrane-based SXC. a The presence of IAV particles in the elution step was indicated by the light scattering signal. b, c Analytical SEC fingerprints of DI244 samples b before and c after SXC purification. Based on the UV signal, the virus purity was 0.7% for the clarified virus harvest and 93.0% for the SXC-purified material. c, d Particle size distributions of DI244 material determined by DCS; d before and e after SXC purificationBack to article page