Fig. 3

Stress response genes are overinduced and metabolic genes are overrepressed in G9a-depleted conditions. a, b Heatmaps showing p values for GO enrichment highlighted in light to dark blue. Not significant terms are highlighted gray. Columns show overinduced (column 1–5, annotated in red) and overrepressed (column 6–10, annotated in purple) gene groups from each dataset. Row colors indicate -log10 of p value (false discovery rate) for enrichment of the indicated GO terms in each dataset. Here we show all selected common GO terms subdivided into functional groups of a stress-related terms: stress response, immune response, cellular signaling and transcription, and additional biological processes; and b metabolic terms: metabolism, carbohydrate metabolism, lipid metabolism, and nucleotide metabolism