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Fig. 4 | BMC Biology

Fig. 4

From: The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra

Fig. 4

HAS-7 inhibits HyWnt3 induced ectopic axis in Xenopus laevis axial duplication assay. a, b Xenopus Wnt8 (XWnt8) mRNA injection induces axis duplication in Xenopus embryos compared to uninjected controls. c HyWnt3 mRNA induces axis duplication comparable to XWnt8 mRNA. d Double injection of HyWnt and HAS-7 mRNAs reverts the axis duplication phenotype. e Quantification of embryos showing a double axis phenotype. Injected mRNA doses were as indicated. n indicates the number of embryos analyzed for each experimental condition. Arrows indicate cement glands. Scale bars = 100 μm.

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