Fig. 7
From: The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra
Mathematical model of HAS-7 function. a Schematic representation of the model. Yellow blocks depict self-containing pattern formation systems consisting of an activator and an inhibitor. b–f Numerical simulations of different experimental scenarios. The blue color corresponds to high levels of HAS-7 expression, the red color to HyWnt3 expression, and the green color indicates the formation of tentacles. The scale of these expression intensities is similar across all simulation plots. g Schematic diagram summarizing the role of HAS-7 in restricting the organizer in steady-state hydras and double axis induction after experimental HAS-7 gene silencing