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Fig. 5 | BMC Biology

Fig. 5

From: Transcriptomic analysis of primate placentas and novel rhesus trophoblast cell lines informs investigations of human placentation

Fig. 5

Transcriptomic comparison of immortalized and primary rhesus trophoblast cells. a PCA plot of RNA-seq gene expression from human (n=6) and rhesus (n=4) bulk placentas, human (n=4) and rhesus (n=4) PBMCs, human primary trophoblasts (n=10), BeWo cells (n=7), and the iRP-D26 (n=2) and iRP-D28A (n=2) cell lines. b Heatmap of HPG expression results. Color scale depicts minimum (purple) and maximum (yellow) one plus Log2 normalized expression values compared across all human and rhesus samples. c Volcano plots of DE analysis results; positive L2FC values represent genes upregulated in iRP-D26 compared to RPT (left; Additional file 12), iRP-D28A compared to RPT (middle; Additional file 13), and iRP-D26 compared to iRP-D28A (right)

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