Fig. 3
From: Innate antiviral defense demonstrates high energetic efficiency in a bony fish
Effects of acute stress (IRAP-associated exhaustive chase and isolated confinement) on sockeye salmon interferon responses and PRV/IHNV load. a Mean (± SE) mRNA transcripts coding for type-1 interferon (ifna), three prominent interferon-stimulated genes (ISGs; myxovirus resistance, viperin, and protein kinase-R), and interleukin-1β (il1b) presented as fold change time-matched mean expression of non-IRAP (tank) averaged across multiple time points relative to their treatment-specific means; saline control (SC), PRV-injected (PRV), IHNV-injected (IHNV); *p < 0.05, **p < 0.01, ***p < 0.001 by 1-way ANOVA with Dunnett’s multiple comparison tests using corrected normalized relative quantities (CNRQ); minimum twofold change suggestive of biological relevance is shaded. b Mean (line) and individual (dot) RNA loads of PRV in the peripheral blood or IHNV in the anterior kidney measured at 0, 1, 4, or 9 weeks post-challenge (wpc)